The U.S. Preventive Services Task Force seeks comments on a draft recommendation statement and draft evidence review on interventions for tobacco smoking cessation in adults, including pregnant persons. The Task Force recommends clinicians ask about tobacco use and connect people to proven, safe methods to help them quit. The evidence is unclear whether e-cigarettes help adults quit smoking. More research is needed on the benefits and harms of using medications to help pregnant people quit. The draft recommendation statement and draft evidence review are available for review and public comment until June 29, 2020.