The U.S. Preventive Services Task Force (USPSTF) released their final recommendation statement on screening for colorectal cancer. The Task Force now recommends that screening start at age 45. The Task Force continues to strongly recommend screening people who are 50 to 75 years old. For adults 76 to 85, the Task Force continues to recommend that the decision to screen be made on an individual basis. To view the recommendation, the evidence and modeling on which it is based, and a summary for clinicians, please go here. The final recommendation statement can also be found in the May 18, 2021 online issue of JAMA.