Expanded Eligibility of Monkeypox Vaccine and Updated Clinical Considerations

The Centers for Disease Control and Prevention announced expanded eligibility for monkeypox vaccination to include pre-exposure prophylaxis (PrEP) for several high risk groups. These groups include:

  • Men who have sex with men, transgender or nonbinary people who in the past 6 months have had any of the following:
  • A new diagnosis of one or more sexually transmitted diseases including acute HIV, chancroid, chlamydia, or gonorrhea
  • More than one sex partner
  • People who in the past 6 months have had any of the following:
  • Sex at a commercial sex venue (like a sex club or bathhouse)
  • Sex at an event, venue, or in an area where monkeypox transmission is occurring.
  • People whose sexual partner identifies with any of the above scenarios
  • People who anticipate experiencing any of the above scenarios

Additionally, preliminary data has shown that those eligible who did not receive the monkeypox vaccine were about 14 times more likely to become infected than those who did receive the monkeypox vaccine. Lastly, CDC has provided additional interim clinical considerations related to intradermal administration of the monkeypox vaccine.