In the February 12 issue of its Morbidity and Mortality Weekly Report, the Centers for Disease Control and Prevention (CDC) report an increase in overdose deaths involving synthetic opioids other than methadone, cocaine, and psychostimulants. During the period studied, 2013 – 2019, synthetic opioid deaths largely consisted of illicitly manufactured fentanyl. In 2019, a total of 70,630 drug overdose deaths occurred, an increase of 4.3 percent over deaths in 2018.